A double-decker bus has overturned, leaving a number of people injured.
The Stagecoach South West bus crashed on the A385 travelling between Totnes and Paignton in Devon at about 11:00 BST.
Police said one person was seriously hurt and more than a dozen suffered minor injuries.
All passengers have now been freed from the bus and cleared from the area by the emergency services, who declared a major incident and closed the road.
It will stay shut in both directions for several hours for “investigation and recovery”, said Gerald Taylor, the area manager for Devon & Somerset Fire and Rescue Service.
A witness said: “It’s like nothing you’ve ever seen up here, there’s emergency vehicles everywhere.”
A spokesman for Stagecoach South West said the company was helping emergency services and its thoughts were with the victims of the crash.
“Safety is our absolute priority and we will be assisting the investigation into the circumstances involved in the incident,” he added.
Several ambulances were sent to the scene, as well as the air ambulance.